(Nitro, BT, p-Nitrotetrazolium Blue; 2, 2´-Di-p-nitrophenyl-5, 5´diphenyl-[3, 3´-dimethoxy-4, 4´-diphenylene] ditetrazolium chloride) C40H30Cl2N10O6 F.W. 817.6 CAS 298-83-9 Approx. 98% (TLC).
Contains up to 10% solvent. A substrate for dehydrogenases and other oxidases Also available in tablet form. Tablet contains 10mg substrate per tablet.
INFO+:Nitro blue tetrazolium is a chemical compound made up of two tetrazole fractions. It is used in immunology for the sensitive detection of alkaline phosphatase
Nitro blue tetrazolium is used in a diagnostic test, in particular for the treatment of granulomatous disease: (or Bridges syndrome, chronic granulomatous disorder and Quie syndrome) and other phagocytic function diseases. In the event of a defect in NADPH oxidase, the phagocyte is unable to produce the reactive oxygen species or the radicals necessary for the destruction of bacteria. As a result, bacteria can grow in the phagocyte. The higher the blue score, the better the cell that produces oxygen species
Storage : 0-5°C