An intensive study from 1992 throughout 2000 has shown that Hemo-De® (d-Limonene) a terpene-based chemical with a pleasant citrus fragrance, was able to replace many of the clinical laboratories toxic reagents, such as carbol-xylene, xylene, ethyl acetate and formalin.
In Parasitology – Hemo-De replaces ethyl acetate in the concentration procedure; Hemo-De replaces carbol-xylene, xylene and formalin in the trichrome procedure.
In Histology – Hemo-De replaces xylene in most all procedures. Hem-De is a superior solvent and Clearing agent that can be used in all tissue processing, deparaffiniating and slide preparation.
– Soluble with alcohol and mounting media
– Biodegradable, non-corrosive, non-flammable (Combustible)
– Contains no benzene and no toluene
– Low toxicity levels
– Minimal tissue shrinkage
– Reasonably fast drying and leaves no residue
In Research and Medical – Hematology, Cytology, Pathology, Microbiology, Histology, Pathology, Hospital
In Mechanical Applications – Cleaning of machine parts, cleaning tools, engines etc.
In Electronic Applications – Circuits boards, electronic components, tools.
General Applications – Clean metal and glass surfaces. Dilute with water can be used to clean all plastic surfaces. Removal of adhesives, glues, tars…
|Chemical name:||d-Limonene (Terpene Hydrocarbon, n.o.s.)|
|Composition:||d-Limonene, CAS [5989-27-5]98.0%
Butylated Hydroxyanisolve (BHA), CAS
|Flash Point (TCC):||121°F (49.4°C)|
|Boiling Point:||349°F (176°C) @ 760mmHg|
|Shipping:||Terpene Hydrocarbons, n.o.s. ID No.
04858003, Flammable Liquid, Group III
W.E. Aldeen and D. Hale. “Use of Hem-De to eliminate toxic agents used for concentration and trichrome staining of intestinal parasites” J. of Clinical Microbiology, July 1992, 1893- 1895, Vol. 30, No. 7
Metzger, Zvi DMD et al. “Gutta-Percha Softening: ‘Hem-De’ as a Xylene Substitute” J. of Endodontics”. 26(7):385-388, July 2000.
Devon C. Hale, MD; et al. “Use of a Single Slide Trichrome- Stained Concentrate for the detection of intestinal Parasites Stained Concentration Procedure for Ova and Parasites” American Journal of Clinical Pathology, Vol. 106, N0. 2. Aug. 1996.
J. M. Miller et al. “Biodegradable, effective substitute for xylene in the Ehrlich indole procedure”. J. of Clinical Microbiology, Aug. 1994, 2028-2030, Vol 32, No 8.
*Hemo-De® is a product of Scientific Solvents.
Technical Data Sheet : Xylene Substitute
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