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High pressure freezing is the most advanced technology when it comes to vitrify a hydrated… Show more (+) High pressure freezing is the most advanced technology when it comes to vitrify a hydrated biological specimen while preserving the ultrastructure. Developed in the 80's [1], the technology evolved progressively to become accessible to a larger community. Still, the sample preparation prior to HPF remains tedious and often comes to advance expertise depending on the specimen [2]. Show less (-) |
