Gomori’s Methenamine Silver for Urate Crystals

Description

APPLICATION:
Urate Stain, Gomori Methenamine Silver Method is designed to demonstrate urates in tissue sections. With abnormal
accumulations found around joints and in soft tissues, this disturbance in uric acid metabolism is known as gout, with collections of urate
crystals referred to as gouty tophi.
Calcium pyrophosphate crystals or pseudogout may also be demonstrated in this procedure. When viewed with a polarizing filter and
red compensator filter, gout and pseudogout can be distinguished.

Stain results:

References:
Sheehan, Dezna C. and Hrapchak, Barbara B.: Theory and Practice of Histotechnology, 2nd Ed.
The C.V. Mosby Company, St. Louis, p.225-226, c. 1980.